IGF-1 LR3 1mg

IGF-1 LR3

Product Overview

IGF-1 LR3 (Long Arg3 Insulin-like Growth Factor-1) is an 83-amino-acid analog of naturally occurring human IGF-1. It features two distinct structural modifications: the substitution of a Glutamic acid for an Arginine at position 3 (hence “Arg3”), and a 13-amino-acid extension piece at the N-terminus (hence “Long”). These precise alterations dramatically decrease the peptide’s affinity for insulin-like growth factor-binding proteins (IGFBP).

Because it escapes binding to these inhibitory proteins, IGF-1 LR3 remains free in experimental environments to interact continuously with the IGF-1 receptor, resulting in an extended biological half-life and vastly increased potency compared to standard IGF-1. In laboratory research, it serves as a highly effective tool for exploring cell survival signaling, tissue repair mechanisms, and the molecular pathways driving skeletal muscle development and metabolic homeostasis.

Research Applications

IGF-1 LR3 is commonly utilized in laboratory settings for investigations involving:

• Cellular proliferation, differentiation, and tissue growth models

• Skeletal muscle hypertrophy and hyperplasia research

• Protein synthesis and nitrogen retention signaling

• Insulin receptor and IGF-1 receptor (IGF-1R) crosstalk

• Cellular repair, wound healing, and musculoskeletal recovery

• Inhibition of apoptosis (programmed cell death) in vitro

• Metabolic regulation and nutrient partitioning pathways

• Preclinical tissue engineering and cell culture optimization

Researchers continue to explore IGF-1 LR3’s interactions with various biological systems to better understand its potential applications in preclinical and translational research environments.

Peptide Information

• Peptide Name: IGF-1 LR3 (Long Arg3 Insulin-like Growth Factor-1)

• Sequence: 83 Amino Acid Recombinant Peptide Analog

• Molecular Classification: Modified Growth Factor Peptide

• Research Category: Cellular Proliferation and Tissue Growth Research Peptide

Storage

Store lyophilized IGF-1 LR3 in a cool, dry environment away from direct light. For long-term storage, refrigeration or freezing is recommended according to established laboratory protocols.

Research Use Only

This product is intended exclusively for laboratory research and analytical purposes.

Not for human consumption. Not for medical, veterinary, household, cosmetic, or food use. This product is not a drug and has not been approved by the U.S. Food and Drug Administration for the diagnosis, treatment, cure, or prevention of any disease. All purchasers are responsible for ensuring compliance with applicable laws and regulations governing research compounds.